Male pattern baldness accounts for more than 95% of hair loss in men. By the age of thirty-five two-thirds of men will experience some degree of hair loss, and by the age of fifty approximately 85% of men have significantly thinning hair.
Contrary to societal belief, most men who suffer from male pattern baldness are extremely unhappy with their situation and would do anything to change it. Hair loss affects every aspect of the hair loss sufferer’s life. It affects interpersonal relationships as well as the professional lives of those suffering. It is not uncommon for men to change their career paths because of their hair loss.
Dihydrotestosterone (DHT), a derivative of the male hormone testosterone, is the primary agent responsible for premature hair loss.
Androgenetic alopecia, commonly called male or female pattern baldness, was only partially understood until the last few decades. For many years, scientists thought that androgenetic alopecia was caused by the predominance of the male sex hormone, testosterone, which women also have in trace amounts under normal conditions. While testosterone is at the core of the balding process, DHT is thought to be the main culprit.
Testosterone converts to DHT with the aid of the enzyme Type II 5-alpha reductase, which is held in a hair follicle’s oil glands. Scientists now believe that it’s not the amount of circulating testosterone that’s the problem but the level of DHT binding to receptors in scalp follicles. DHT shrinks hair follicles, making it impossible for healthy hair to survive.
The hormonal process of testosterone converting to DHT, which then harms hair follicles, happens in both men and women. Under normal conditions, women have a minute fraction of the level of testosterone that men have, but even a lower level can cause DHT- triggered hair loss in women. And certainly when those levels rise, DHT is even more of a problem.
Other causes of hair loss include:
Hair Loss Treatments
Specialised hair loss solutions are formulated in our laboratory. We use higher strengths of minoxidil which thicken and lengthen hair follicles. We use a variety a DHT blockers which prevents the formation of DHT, which as discussed above, is the main hormonal culprit in hair loss. We also use retinoic acid which promotes hair growth in combination with minoxidil to increases cell turnover thus increasing the rate of hair growth. It also increases the absorption of minoxidil so hair growth can appear faster.
It takes 4-6 months of application to see noticeable hair thickening and lengthening.
Contact us for further information or to book an appointment with the compounding pharmacist.